Small ubiquitin-related modifier 2

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August undefined, 2024

WebMar 21, 2024 · SUMO2 (Small Ubiquitin Like Modifier 2) is a Protein Coding gene. Diseases associated with SUMO2 include Phlyctenulosis . Among its related pathways are Transport of the SLBP independent Mature mRNA and Homology Directed Repair . Gene Ontology (GO) annotations related to this gene include RNA binding and SUMO transferase activity . WebJul 26, 2024 · together, this work shows that small ubiquitin-related modifier-2 modification of NF-jB2/p65 is essential for the survival of Brucella abortus 2308 inside macrophages. …

Small Ubiquitin-related Modifier (SUMO)-specific Proteases

WebJun 4, 2024 · Ubiquitin is a small (8.6 kDa) 76-residue regulatory protein which is found ‘ubiquitously’ in the cytoplasm and nucleus of eukaryotic cells and is a post-translational … UniProt P61956 · SUMO2_HUMAN Protein Small ubiquitin-related modifier 2 Gene SUMO2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 95 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST … See more This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. 1. Name1 2. See … See more marie pila collège

Small ubiquitin-related modifier 2 affects the intracellular survival ...

WebAug 10, 2008 · Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men Petrice W. Brown, KeumSil Hwang, Peter N. Schlegel, Patricia L. Morris WebMay 1, 2009 · The present study aimed to produce and pathophysiologically evaluate the metallothionein (MT) fusion protein. A recombinant plasmid containing DNA segment coding the pET-glutathione transferase (GST)-small ubiquitin-related modifier (SUMO)-MT fusion protein was inserted into Escherichia coli for expression. The expression level of … WebSmall ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, signal transduction, … marie pila carpentras college

Hepatic Small Ubiquitin‐Related Modifier …

In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. This process is called SUMOylation (sometimes written sumoylation). SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional re… WebOct 12, 2015 · The mouse small ubiquitin-like modifier-2 (SUMO-2) inhibits interleukin-12 (IL-12) production in mature dendritic cells by blocking the translocation of the p65 subunit … marie pimentel md gilbertWebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, … dalinda sanchez

"WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. " - Small ubiquitin-related modifier 2

Small ubiquitin-related modifier 2

WebSmall ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein family (1). The covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to … WebAbstract. Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking ...

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WebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO … WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase activity)andremovingconjugatedSUMOfromtargets(isopep …

WebFeb 22, 2005 · Importantly, Sp100 and PML are both covalently linked to small ubiquitin-related modifiers (SUMOs). Therefore, we investigated whether SUMO proteins are independent autoantigens in PBC and studied 99 PBC sera samples for reactivity against NDs, PML, and Sp100, as well as against SUMO-2 and SUMO-1 recombinant proteins. WebMay 2, 2024 · Small ubiquitin-related modifier (SUMO)–specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, …

WebOverview Product name Anti-Sumo 2 + Sumo 3 antibody See all Sumo 2 + Sumo 3 primary antibodies Description Rabbit polyclonal to Sumo 2 + Sumo 3 Host species Rabbit Specificity Recognises 2 bands representing Sumo 2 and Sumo 3 at 15 and 18kDa in Hela Nuclear extract by Western blotting. Tested applications WebSUMO (small ubiquitin-related modifier) proteins are ∼ 10-kD polypeptides that function as reversible post-translational protein modifiers. They form isopeptide bonds with ɛ-amino …

WebSmall ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm. [ 1] [ 2] Immunogen human SUMO3 fusion protein Application Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and …

WebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. marie pisciottaWebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ... dalinda tizzaniWebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the … marie pitts obituaryWebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in … marie pintoWebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase ... SUMO protease but functions on another small ubiquitin-re-latedproteinknownasNedd8(6,7).Thedefiningcharacteristic ... SUMO, small ubiquitin-like modifier; AFC, 7-amino-4-trifluoromethyl coumarin; DUB, de-ubiquitinating enzyme; marie pizzo marie pirillo dermatologistWebMar 15, 2012 · SUMO (small ubiquitin-related modifier) conjugation is a reversible three-step process of protein post-translational modifications mediating protein-protein interactions, subcellular compartmentalization and regulation of transcriptional events. Among divergent transcription factors regulated by SUMOylation and deSUMOylation, the … dal industriservice ab