Web18 okt. 2010 · Summary: The first clinical trials on a new investigational drug being developed to treat infections caused by hepatitis C virus have been successfully completed. Completion of the initial phase... Web15 aug. 2010 · The potency of the lead compound INX-08189 was shown to be consistent with intracellular 2'-C-methyl guanosine triphosphate levels in primary human hepatocytes. The separated diastereomers of INX-08189 were shown to have similar activity in the replicon assay and were also shown to be similar substrates for enzyme processing.
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