Homoaconitate hydratase
WebFungi produce α-aminoadipate, a precursor for penicillin and lysine via the α-aminoadipate pathway. Despite the biotechnological importance of this pathway, the essential isomerization of homocitrate via homoaconitate to homoisocitrate has hardly been studied. Therefore, we analysed the role of homo … Web21 aug. 2014 · Three sex-specific proteins were isolated and identified using CAF-MALDI mass spectrometry and RACE-PCR. Among them, a male gamete-specific homoaconitate hydratase (HACN) and a female gamete-specific succinate semialdehyde dehydrogenase (SSADH) were predicted to be the genes involved in mitochondrial metabolic pathways.
Homoaconitate hydratase
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WebThe role of aconitate hydratase and structurally similar iron-regulatory protein in maintenance of homeostasis of cell iron is described. Information on modifications of … Web24 okt. 2008 · Along with the homologous 2-methyl-cis-aconitate hydratase and dimethylmalate dehydratase proteins, those HACN proteins catalyze only half of an aconitase-like reaction (16, 17). The HACN enzymes catalyze the hydration of cis-homoaconitate to form homoisocitrate (18).
Web19 nov. 2004 · Recent studies have implied that the isopropylmalate isomerase small subunit of the hyperthermophilic archaea Pyrococcus horikoshii (PhIPMI-s) functions as isopropylmalate isomerase in the leucine biosynthesis pathway, and as homoaconitase (HACN) in the lysine biosynthesis pathway via alpha-aminoadi … Webhomoaconitate hydratase; homoaconitase; cis-homoaconitase; HACN; Lys4; LysF; 2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase (incorrect) Class Lyases; Carbon-oxygen lyases; Hydro-lyases BRITE hierarchy Sysname (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [ (Z)-but-1-ene-1,2,4-tricarboxylate-forming] Reaction (IUBMB)
WebHomoaconitate hydratase (homoaconitase) is an enzyme from the alpha-aminoadipate pathway of lysine biosynthesis, and has been identified in higher fungi and several … WebHomoaconitate hydratase (homoaconitase) ... (2R)-homocitrate to cis-homoaconitate, and the hydration of the later to (1R,2S)-homoisocitrate. homoaconitase from Thermus thermophilus is a dimeric protein, encoded by two genes, lysT and lysU, which were initially named hacA and hacB.
WebHomoaconitate hydratase Imported. Gene names. Name. aksA Imported. ORF names. J6P91_01040 Imported. Organism names. Organism. Methanobrevibacter sp Imported. Taxonomic identifier. 66852 NCBI. Taxonomic lineage. Archaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > …
WebCatalyzes the isomerization of citrate to isocitrate via cis-aconitate, a step in the citric acid cycle. Can also provide minor contributions to the reversible dehydration of (R) … neel aviation lakeland flWebAconitases are iron-sulfur proteins which catalyze the reversible isomerization of citrate and isocitrate via cis -aconitate. While in mitochondria aconitase is part of the … ithaca gun company king ferry nyWebAconitase (aconitate hydratase; EC 4.2.1.3), which catalyzes isomerization of citrate to isocitrate via cis -aconitate in the TCA cycle, is an enzyme highly sensitive to irreversible … neela thotaWeb3 mrt. 2014 · Belongs in the α-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36, homoaconitate hydratase. The enzyme also acts with oxaloacetate as substrate, but more slowly. Form. Liquid or lyophilized powder. Enzyme Commission Number. EC 2.3.3.14. CAS No. 9075-60-9. Storage. neela waters beach homestayWebBRENDA - The Comprehensive Enzyme Information System. 4.2.1.36: homoaconitate hydratase. This is an abbreviated version! For detailed information about homoaconitate hydratase, go to the full flat file. ithaca gymsWebFungi have evolved a unique α-amino-adipate pathway for lysine biosynthesis. The fungal-specific enzyme homoaconitate hydratase from this pathway is moderately similar … neela wickramasinghe thun sithaWebThe enzyme homoaconitate hydratase catalyzes the chemical reaction. For faster navigation, this Iframe is preloading the Wikiwand page for Homoaconitate hydratase. … neela wickramasinghe husband